RB1-inducible coiled-coil protein 1, FAK family kinase-interacting protein of 200 kDa, FIP200, RB1CC1, KIAA0203, RBICC
Product description
The protein encoded by this gene interacts with signaling
pathways to coordinately regulate cell growth, cell proliferation,
apoptosis, autophagy, and cell migration. This tumor suppressor
also enhances retinoblastoma 1 gene expression in cancer cells.
Alternative splicing results in multiple transcript variants
encoding distinct isoforms.1) Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Immunogen
This RB1CC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-515 amino acids from the Central region of human RB1CC1.
Western blot analysis in mouse brain tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.