Application
Antibody used in WB on Human HepG2 at 1 ug/ml.| Product Name | RORC Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RORC, MGC129539, NR1F3, RORG, RZRG, TOR, RZR-GAMMA |
| Product description | RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.1) Huang, Z., (2007) Expert Opin. Ther. Targets 11 (6), 737-743. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RORC. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| RORC antibody can be used for detection of RORC by ELISA at 1:1562500. RORC antibody can be used for detection of RORC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RORC |
|---|---|
| Alternative Names | RORC MGC129539 NR1F3 RORG RZRG TOR RZR-GAMMA |
| Molecular Weight(MW) | 56 kDa |
| Entrez Gene | 6097 |
|---|---|
| Protein Accession | NP_001001523 |
Application
Antibody used in WB on Human HepG2 at 1 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | RORC antibody can be used for detection of RORC by ELISA at 1:1562500. RORC antibody can be used for detection of RORC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store RORC antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
