Replication protein A 30 kDa subunit, RP-A p30, Replication factor A protein 4, RF-A protein 4, RPA4
Product description
This gene encodes a single-stranded DNA-binding protein
that is the 30-kDa subunit of the replication protein A complex.
Replication protein A is an essential factor for DNA double-strand
break repair and cell cycle checkpoint activation. The encoded
protein localizes to DNA repair foci and may be involved in the
cellular DNA damage response. This protein may also play a role in
inhibiting viral replication.1) Kemp, M.G., et al. J. Biol. Chem. 285(7):4788-4797(2010)
Immunogen
This RPA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-261 amino acids from the C-terminal region of human RPA4.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.