Application
Western blot analysis of RRAS2 in Jurkat cell lysate with RRAS2 antibody at (A) 1 and (B) 2 μg/mL| Product Name | RRAS2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RRAS2 Antibody: TC21, TC21, Ras-related protein R-Ras2, Ras-like protein TC21 |
| Product description | RRAS2 Antibody: Activating mutations and overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55–60%. RRAS2 is a small GTPbinding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.1) Ehrhardt A, Ehrhardt GR, Guo X, et al. Ras and relatives--job sharing and networking keep an old family together. Exp. Hematol. 2002; 30:1089-106. |
| Immunogen | Rabbit polyclonal RRAS2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human RRAS2. The immunogen is located within the last 50 amino acids of RRAS2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| RRAS2 antibody can be used for detection of RRAS2 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RRAS2 |
|---|---|
| Alternative Names | RRAS2 Antibody: TC21 TC21 Ras-related protein R-Ras2 Ras-like protein TC21 |
| Molecular Weight(MW) | 22 kDa |
| Tissue Specificity | Two isoforms of RRAS2 exists as a result of alternative splicing event. |
Application
Western blot analysis of RRAS2 in Jurkat cell lysate with RRAS2 antibody at (A) 1 and (B) 2 μg/mL| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | RRAS2 antibody can be used for detection of RRAS2 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | RRAS2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | RRAS2 Antibody is supplied in PBS containing 0.02% sodium azide. |
