Application
Western blot analysis in Y79,A2058,CEM cell line lysates(35ug/lane)| Product Name | SAP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Prosaposin, Proactivator polypeptide, Saposin-A, Protein A, Saposin-B-Val, Saposin-B, Cerebroside sulfate activator, CSAct, Dispersin, Sphingolipid activator protein 1, SAP-1, Sulfatide/GM1 activator, Saposin-C, A1 activator, Co-beta-glucosidase, Glucosylc |
| Product description | PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.1) Gunia,S., Virchows Arch. 454 (5), 573-579 (2009) |
| Immunogen | This SAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the Central region of human SAP. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | PSAP |
|---|---|
| Alternative Names | Prosaposin Proactivator polypeptide Saposin-A Protein A Saposin-B-Val Saposin-B Cerebroside sulfate activator CSAct Dispersin Sphingolipid activator protein 1 SAP-1 Sulfatide/GM1 activator Saposin-C A1 activator Co-beta-glucosidase Glucosylc |
| Molecular Weight(MW) | 58 kDa |
Application
Western blot analysis in Y79,A2058,CEM cell line lysates(35ug/lane)| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
