Nonvoltage-gated, amiloride-sensitive, sodium channels
control fluid and electrolyte transport across epithelia in many
organs. These channels are heteromeric complexes consisting of 3
subunits: alpha, beta, and gamma. This gene encodes the beta
subunit, and mutations in this gene have been associated with
pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This SCNN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-332 amino acids from the Central region of human SCNN1B.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.