Application
Antibody used in IHC on Human kidney.Application
Antibody used in WB on Human HepG2 at 1.25 ug/ml.| Product Name | SDCBP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SDCBP, MDA-9, ST1, SYCL, TACIP18 |
| Product description | SDCBP was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.1) Boukerche, H., (2005) Cancer Res. 65 (23), 10901-10911. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SDCBP. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| SDCBP antibody can be used for detection of SDCBP by ELISA at 1:312500. SDCBP antibody can be used for detection of SDCBP by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | DogHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SDCBP |
|---|---|
| Alternative Names | SDCBP MDA-9 ST1 SYCL TACIP18 |
| Molecular Weight(MW) | 32 kDa, 32 kDa, 32 kDa, 32 kDa, 32 kDa |
| Entrez Gene | 6386 |
|---|---|
| Protein Accession | NP_001007068 |
Application
Antibody used in IHC on Human kidney.
Application
Antibody used in WB on Human HepG2 at 1.25 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | SDCBP antibody can be used for detection of SDCBP by ELISA at 1:312500. SDCBP antibody can be used for detection of SDCBP by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store SDCBP antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
