Application
Formalin-fixed and paraffin-embedded human Thymus tissue reacted with SENP1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.Application
Western blot analysis of SENP1 polyclonal antibody in whole HL60 cell lysate: SENP1 was detected using purified Pab.| Product Name | SENP1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.1) Gong, L., et al., J. Biol. Chem. 275(5):3355-3359 (2000). Bailey, D., et al., J. Gen. Virol. 83 (Pt 12), 2951-2964 (2002). |
| Immunogen | This SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human SENP1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Gene Symbol | SENP1 |
|---|---|
| Alternative Names | Sentrin-specific protease 1 Sentrin/SUMO-specific protease SENP1 SENP1 |
| Molecular Weight(MW) | 73 kDa |
Application
Formalin-fixed and paraffin-embedded human Thymus tissue reacted with SENP1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.
Application
Western blot analysis of SENP1 polyclonal antibody in whole HL60 cell lysate: SENP1 was detected using purified Pab.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
