SEPT6 is a member of the septin family of GTPases. Members of this family are required for cytokinesis.This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.1) Ding, X., (2007) J. Biochem. Mol. Biol. 40 (6), 973-978.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human Septin 6.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
Septin 6 antibody can be used for detection of Septin 6 by ELISA at 1:62500. Septin 6 antibody can be used for detection of Septin 6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Septin 6 antibody can be used for detection of Septin 6 by ELISA at 1:62500. Septin 6 antibody can be used for detection of Septin 6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store Septin 6 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt