Application
Immunohistochemistry staining of SGK3 in kidney tissue using SGK3 Antibody.| Product Name | SGK3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | SGKL/SGK3, also known as CISK for cytokine-independent survival kinase, is a SGK type protein kinase. The protein contains a lipid-binding phox homology (PX) domain, which is required for targeting SGKL/SGK3 protein to the endosomal compartment. SGKL/SGK3 functions downstream of the phosphoinositide 3-kinase (PI3K) cascade and has been implicated in cell survival. The protein has been shown to be phosphorylated and activated by 3-phosphoinositide-dependent protein kinase 1 (PDK1), and to a lesser extent insulin-like growth factor-1, in vitro. Activated SGKL/SGK3 has been shown to phosphorylate glycogen synthase kinase 3 beta (GSK-3beta) in vitro. |
| Immunogen | SGK3 antibody was raised against a peptide located in the C-Terminal domain of SGK3 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC |
| SGK3 antibody can be used in immunohistochemistry starting at 14 - 28 μg/mL. | |
| Species Reactivity | GibbonGorillaHumanMonkeyOrangutanRabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SGK3 |
|---|---|
| Alternative Names | SGK3 CISK SGKL |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SGK1 (59%). |
Application
Immunohistochemistry staining of SGK3 in kidney tissue using SGK3 Antibody.| Application Notes | SGK3 antibody can be used in immunohistochemistry starting at 14 - 28 μg/mL. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | SGK3 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
