Application
Western blot analysis of extracts from COS7 cells treated with EGF using SHP-1 (Phospho-Tyr564) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | SHP-1 (phospho Tyr564) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.1) Yi T., Mol. Cell. Biol. 12:836-846(1992). |
| Immunogen | SHP-1 (phospho Tyr564) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 564 (D-V-Y (p)-E-N) derived from Human SHP-1. |
| Modification | p-Tyr564 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTPN6 |
|---|---|
| Alternative Names | HCP HCPH PTN6 PTP1C SHP1 |
| Molecular Weight(MW) | 70 kDa |
| Tissue Specificity | The antibody detects endogenous levels of SHP-1 only when phosphorylated at tyrosine 564. |
| Entrez Gene | 5777 |
|---|---|
| Protein Accession | NP_002822.2 |
Application
Western blot analysis of extracts from COS7 cells treated with EGF using SHP-1 (Phospho-Tyr564) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
