Mitochondrial carnitine/acylcarnitine carrier protein, Carnitine/acylcarnitine translocase, CAC, Solute carrier family 25 member 20, SLC25A20, CAC, CACT
Product description
This gene product is one of several closely related
mitochondrial-membrane carrier proteins that shuttle substrates
between cytosol and the intramitochondrial matrix space. This
protein mediates the transport of acylcarnitines into mitochondrial
matrix for their oxidation by the mitochondrial fatty
acid-oxidation pathway. Mutations in this gene are associated with
carnitine-acylcarnitine translocase deficiency, which can cause a
variety of pathological conditions such as hypoglycemia, cardiac
arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and
is usually lethal in new born and infants.1) Tachibana, K., et al. Biochem. Biophys. Res. Commun. 389(3):501-505(2009)
Immunogen
This SLC25A20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from the C-terminal region of human SLC25A20.
Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.