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SLC27A2 Antibody

Catalog Number:OM291439
OM291439
Discount Price
OM291439-100ul
1~2 Week
100ul
OM291439-50ul
50ul
OM291439-20ul
20ul
1~2 Week
Product Profile
Product Name SLC27A2 Antibody
Antibody Type Primary Antibodies
Product description

SLC27A2 is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.1) Mihalik, S.J., (2002) J. Biol. Chem. 277 (27), 24771-24779.

 
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC27A2.
Modification Acetylated
Key Feature
Clonality Polyclonal
Isotype Cocktail
Host Species Rabbit
Tested Applications ELISAIHCWB
WB:1:500~1:2000
IHC:1:50~1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SLC27A2
Alternative Names SLC27A2
ACSVL1
FACVL1
FATP2
HsT17226
VLACS
VLCS
hFACVL1
Molecular Weight(MW) 70 kDa
Database Links
Entrez Gene 11001
Protein Accession NP_003636
Application

Application

Antibody used in IHC on Human Liver.

Application

Antibody used in WB on Human HeLa cells at 1 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).

Application

Antibody used in WB on Human HeLa at 1 ug/ml.

Application

Antibody used in IHC on Human Liver.

WB

mRNA expression of FATP2 (a) and FABP1 (b) in livers of female and male mice; protein expression of FATP2 (c) and FABP1 (d) in livers of female mice.
Positive Control HeLa Cell Lysate
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store SLC27A2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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References(1)