Application
Immunofluorescence of SLC29A2 in human bladder tissue with SLC29A2 antibody at 20 μg/ml.Application
Immunohistochemistry of SLC29A2 in human bladder tissue with SLC29A2 antibody at 2.5 μg/mL.Application
Western blot analysis of SLC29A2 in human bladder tissue lysate with SLC29A2 antibody at 1 μg/ml.| Product Name | SLC29A2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Solute carrier family 29 member 2, Equilibrative nucleoside transporter 2, ENT2, DER12, HNP36 |
| Product description | SLC29A2 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A2 is a transmembrane glycoprotein that mediates the cellular uptake of nucleosides from the surrounding medium (3). As a nucleoside transporter, SLC29A2 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4).1) Williams JB and Lanahan AA. A mammalian delayed-early response gene encodes HNP36, a novel, conserved nucleolar protein. Biochim. Biophys. Res. Commun. 1995; 213:325-33. |
| Immunogen | SLC29A2 antibody was raised against a 19 amino acid peptide near the center of human SLC29A2. The immunogen is located within amino acids 250 - 300 of SLC29A2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| SLC29A2 antibody can be used for detection of SLC29A2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SLC29A2 |
|---|---|
| Alternative Names | Solute carrier family 29 member 2 Equilibrative nucleoside transporter 2 ENT2 DER12 HNP36 |
| Molecular Weight(MW) | Predicted: 50 kDa Observed: 50 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Rat: (100%) |
| Tissue Specificity | SLC29A2 antibody is human specific. SLC29A2 antibody is predicted to not cross-react with other SLC29 proteins. |
Application
Immunofluorescence of SLC29A2 in human bladder tissue with SLC29A2 antibody at 20 μg/ml.
Application
Immunohistochemistry of SLC29A2 in human bladder tissue with SLC29A2 antibody at 2.5 μg/mL.
Application
Western blot analysis of SLC29A2 in human bladder tissue lysate with SLC29A2 antibody at 1 μg/ml.| Positive Control | 1) Cat. No. 1310 - Human Bladder Tissue Lysate |
|---|---|
| Application Notes | SLC29A2 antibody can be used for detection of SLC29A2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | SLC29A2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | SLC29A2 antibody is supplied in PBS containing 0.02% sodium azide. |
