Application
Western blot analysis in CEM cell line lysates (35ug/lane).| Product Name | SMC3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.1) Pie, J., et al. Am. J. Med. Genet.152A (4), 924-929 (2010) : |
| Immunogen | This SMC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-430 amino acids from the Central region of human SMC3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SMC3 |
|---|---|
| Alternative Names | Structural maintenance of chromosomes protein 3 SMC protein 3 SMC-3 Basement membrane-associated chondroitin proteoglycan Bamacan Chondroitin sulfate proteoglycan 6 Chromosome-associated polypeptide hCAP SMC3 BAM BMH CSPG6 SMC3L1 |
| Molecular Weight(MW) | 142 kDa |
Application
Western blot analysis in CEM cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
