SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box.1) Hirsch, H.A., et al., (2000) Mol. Cell. Biol. 20 (24), 9182-9191.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SNAPC3.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
SNAPC3 antibody can be used for detection of SNAPC3 by ELISA at 1:1562500. SNAPC3 antibody can be used for detection of SNAPC3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Antibody used in WB on Human Small Intestine at 2.5 ug/ml.
Positive Control
1) Cat. No. XBL-10420 - Fetal Small Intestine Tissue Lysate
Application Notes
SNAPC3 antibody can be used for detection of SNAPC3 by ELISA at 1:1562500. SNAPC3 antibody can be used for detection of SNAPC3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SNAPC3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt