SOX3 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.1) Savare, J., et al., (2005) Mol. Biol. Cell 16 (6), 2660-2669.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SOX3.
Modification
Acetylated
Key Feature
Clonality
Polyclonal
Isotype
Cocktail
Host Species
Rabbit
Tested Applications
ELISAICC/IFIHC-FIHC-PWB
SOX3 antibody can be used for detection of SOX3 by ELISA at 1:312500. SOX3 antibody can be used for detection of SOX3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
SOX3 antibody can be used for detection of SOX3 by ELISA at 1:312500. SOX3 antibody can be used for detection of SOX3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SOX3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt