Application
Antibody used in IHC on Human Heart.Application
Antibody used in WB on Human Fetal Kidney at 1 ug/ml.Application
Antibody used in IHC on Human Testis.Application
Antibody used in IHC on Human Heart.| Product Name | SOX4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SOX4, EVI16 |
| Product description | SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.1) Hoser, M., (2007) J. Neurosci. 27 (20), 5495-5505 . |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SOX4. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| SOX4 antibody can be used for detection of SOX4 by ELISA at 1:62500. SOX4 antibody can be used for detection of SOX4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SOX4 |
|---|---|
| Alternative Names | SOX4 EVI16 |
| Molecular Weight(MW) | 47 kDa |
Application
Antibody used in IHC on Human Heart.
Application
Antibody used in WB on Human Fetal Kidney at 1 ug/ml.
Application
Antibody used in IHC on Human Testis.
Application
Antibody used in IHC on Human Heart.| Positive Control | 1) Cat. No. XBL-10408 - Fetal Kidney Tissue Lysate |
|---|---|
| Application Notes | SOX4 antibody can be used for detection of SOX4 by ELISA at 1:62500. SOX4 antibody can be used for detection of SOX4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store SOX4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
