Serine palmitoyltransferase 3, 2.3.1.50, Long chain base biosynthesis protein 2b, LCB2b, Long chain base biosynthesis protein 3, LCB 3, Serine-palmitoyl-CoA transferase 3, SPT 3, SPTLC3, C20orf38, SPTLC2L
Product description
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, while the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.1) Hornemann T.,et al.J. Biol. Chem. 281:37275-37281(2006).
Immunogen
This SPTLC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 503-545 amino acids from human SPTLC3.
Serine palmitoyltransferase 3 2.3.1.50 Long chain base biosynthesis protein 2b LCB2b Long chain base biosynthesis protein 3 LCB 3 Serine-palmitoyl-CoA transferase 3 SPT 3 SPTLC3 C20orf38 SPTLC2L
Western Blot at 1:2000 dilution Lane 1: human heart lysate Lane 2: human kidney lysate Lane 3: human uterus lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:2000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.