Application
Antibody used in WB on Human Jurkat cells at 0.25 ug/ml.Application
Antibody used in WB on Jurkat 2.0 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).Application
Antibody used in IHC on Human Prostate at 5.0 ug/ml.Application
Antibody used in IHC on Human Kidney at 4.0-8.0 ug/ml.Application
Antibody used in IHC on Human Liver at 5 ug/ml.| Product Name | SSB Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SSB, La, LARP3, La/SSB |
| Product description | SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU (OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU (OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006).1) Teplova, M., (2006) Mol. Cell 21 (1), 75-85. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SSB. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| SSB antibody can be used for detection of SSB by ELISA at 1:312500. SSB antibody can be used for detection of SSB by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | DogHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SSB |
|---|---|
| Alternative Names | SSB La LARP3 La/SSB |
| Molecular Weight(MW) | 45 kDa |
Application
Antibody used in WB on Human Jurkat cells at 0.25 ug/ml.
Application
Antibody used in WB on Jurkat 2.0 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).
Application
Antibody used in IHC on Human Prostate at 5.0 ug/ml.
Application
Antibody used in IHC on Human Kidney at 4.0-8.0 ug/ml.
Application
Antibody used in IHC on Human Liver at 5 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | SSB antibody can be used for detection of SSB by ELISA at 1:312500. SSB antibody can be used for detection of SSB by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store SSB antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
