Application
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).| Product Name | ST6GALNAC4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase, NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase, ST6GalNAc IV, ST6GalNAcIV, Sialyltransferase 3C, SIAT3-C, Sialyltransferase 7D, SIAT7-D |
| Product description | The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene.1) Yoshino, H., et al. Brain Res. 1227, 216-220 (2008) : |
| Immunogen | This ST6GALNAC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human ST6GALNAC4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ST6GALNAC4 |
|---|---|
| Alternative Names | Alpha-N-acetyl-neuraminyl-2 3-beta-galactosyl-1 3-N-acetyl-galactosaminide alpha-2 6-sialyltransferase NeuAc-alpha-2 3-Gal-beta-1 3-GalNAc-alpha-2 6-sialyltransferase ST6GalNAc IV ST6GalNAcIV Sialyltransferase 3C SIAT3-C Sialyltransferase 7D SIAT7-D |
| Molecular Weight(MW) | 34 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Mouse |
Application
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
