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STAMBP Antibody

Catalog Number:OM292300
OM292300
Discount Price
OM292300-100ul
1~2 Week
100ul
OM292300-50ul
50ul
OM292300-20ul
20ul
1~2 Week
Product Profile
Product Name STAMBP Antibody
Antibody Type Primary Antibodies
Antigen Alias STAM-binding protein, 3419-, Associated molecule with the SH3 domain of STAM, Endosome-associated ubiquitin isopeptidase, STAMBP, AMSH
Product description Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.1) Sierra, M.I., et al. J. Biol. Chem. 285(18):13990-14004(2010)
Immunogen This STAMBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-383 amino acids from the C-terminal region of human STAMBP.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol STAMBP
Alternative Names STAM-binding protein
3419-
Associated molecule with the SH3 domain of STAM
Endosome-associated ubiquitin isopeptidase
STAMBP
AMSH
Molecular Weight(MW) 48 kDa
Database Links
Entrez Gene 10617
Protein Accession O95630
Application

Application

STAMBP Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).

Application

Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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