Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.1) Heim M H, (1999) J Recept Signal Transduct Res. 19: 75-120. Takeda K, et al. (1997) Proc Natl Acad Sci USA. 94: 3801-3804. Catlett-Falcone R, et al. (1999) Immunity. 10: 105-115. Garcia R, et al. (1998) J Biomed Sci. 5: 79-85. Bromberg J F, et al. (1999) Cell. 98: 295-303.
Immunogen
STAT3 (Ab-727) antibody was raised against a peptide sequence around aa. 725~729 (P-M-S-P-R) derived from Human STAT3.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHCWB
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100: