Application
Immunofluorescence of STAT3 in human small intestine tissue with STAT3 antibody at 20 μg/ml.Application
Western blot analysis of STAT3 in human small intestine tissue lysate with STAT3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.Application
Immunohistochemistry of STAT3 in human small intestine tissue with STAT3 antibody at 5 μg/ml.| Product Name | STAT3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STAT3 Antibody: APRF, HIES, APRF, Signal transducer and activator of transcription 3, Acute-phase response factor |
| Product description | STAT3 Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, and STAT6), STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile. STAT3 signals are pivotal to the proliferation and differentiation of neural stem cells and also participate in neuronal regeneration and cancers of the nervous system.1) Schaefer TS, Sanders LK, and Nathans D. Cooperative transcriptional activity of Jun and Stat3b, a short form of Stat3. Proc. Natl. Acad. Sci. USA 1995; 92:9097-101. |
| Immunogen | Rabbit polyclonal STAT3 antibody was raised against a 19amino acid peptide near the amino terminus of human STAT3. The immunogen is located within amino acids 170 - 220 of STAT3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| STAT3 antibody can be used for detection of STAT3 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STAT3 |
|---|---|
| Alternative Names | STAT3 Antibody: APRF HIES APRF Signal transducer and activator of transcription 3 Acute-phase response factor |
| Molecular Weight(MW) | Predicted: 85 kDa |
| Sequence Similarities | 2) Cat. No. 11-801 - Human Small Intestine Tissue Slide |
Application
Immunofluorescence of STAT3 in human small intestine tissue with STAT3 antibody at 20 μg/ml.
Application
Western blot analysis of STAT3 in human small intestine tissue lysate with STAT3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Application
Immunohistochemistry of STAT3 in human small intestine tissue with STAT3 antibody at 5 μg/ml.| Positive Control | 1) Cat. No. 1308 - Human Small Intestine Tissue Lysate |
|---|---|
| Application Notes | STAT3 antibody can be used for detection of STAT3 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | STAT3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | STAT3 Antibody is supplied in PBS containing 0.02% sodium azide. |
