STAT4 is a transcription factor involved in promoting cell-mediated immunity. It is a key molecule in the intracellular signal transduction cascade activated in response to IL-12 stimulation. Following phosphorylation in response to IL-12 or IFN-alpha STAT4 dimerizes, translocates to the nucleus, and activates gene expression.
Immunogen
STAT4 antibody was raised against recombinant (partial), N-Terminal region of STAT4 (Human).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
STAT4 antibody can be used in immunohistochemistry starting at 10 μg/mL, immunoprecipitation, and flow cytometry starting at 1:50 - 1:100.: