Application
Antibody used in IHC on Human prostate at 5 ug/ml.Application
Antibody used in IHC on Human prostate at 5 ug/ml.Application
Antibody used in WB on Human 293T at 1 ug/ml.Application
Antibody used in IHC on Human Testis at 5 ug/ml.Application
Antibody used in IHC on Human placenta at 5 ug/ml.Application
Antibody used in IHC on Human testis at 5 ug/ml.| Product Name | STAT5B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STAT5B, STAT5 |
| Product description | The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Mohankumar, K.M., (2008) Endocrinology 149 (5), 2219-2229. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STAT5B. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| STAT5B antibody can be used for detection of STAT5B by ELISA at 1:1562500. STAT5B antibody can be used for detection of STAT5B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STAT5B |
|---|---|
| Alternative Names | STAT5B STAT5 |
| Molecular Weight(MW) | 90 kDa |
Application
Antibody used in IHC on Human prostate at 5 ug/ml.
Application
Antibody used in IHC on Human prostate at 5 ug/ml.
Application
Antibody used in WB on Human 293T at 1 ug/ml.
Application
Antibody used in IHC on Human Testis at 5 ug/ml.
Application
Antibody used in IHC on Human placenta at 5 ug/ml.
Application
Antibody used in IHC on Human testis at 5 ug/ml.| Positive Control | 1) Tranfected 293T Cell Lysate |
|---|---|
| Application Notes | STAT5B antibody can be used for detection of STAT5B by ELISA at 1:1562500. STAT5B antibody can be used for detection of STAT5B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store STAT5B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
