Application
Antibody used in WB on recombinant STAT6 protein at 0.2-1 ug/ml.| Product Name | STAT6 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C |
| Product description | STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.1) Blanchard, C., (2005) Int. J. Biochem. Cell Biol. 37 (12), 2559-2573. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STAT6. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| STAT6 antibody can be used for detection of STAT6 by ELISA at 1:62500. STAT6 antibody can be used for detection of STAT6 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STAT6 |
|---|---|
| Alternative Names | STAT6 D12S1644 IL-4-STAT STAT6B STAT6C |
| Molecular Weight(MW) | 94 kDa |
Application
Antibody used in WB on recombinant STAT6 protein at 0.2-1 ug/ml.| Application Notes | STAT6 antibody can be used for detection of STAT6 by ELISA at 1:62500. STAT6 antibody can be used for detection of STAT6 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store STAT6 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
