This gene is a member of the suppressor of variegation 3-9
homolog family and encodes a protein with a chromodomain and a
C-terminal SET domain. This nuclear protein moves to the
centromeres during mitosis and functions as a histone
methyltransferase, methylating Lys-9 of histone H3. Overall, it
plays a vital role in heterochromatin organization, chromosome
segregation, and mitotic progression.1) Chen, L., et al. EMBO J. 29(15):2538-2552(2010)
Immunogen
This SUV39H1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human SUV39H1.
Western Blot at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.