Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level1) Diviya Sinha, et, al. (2005) Am J Physiol Renal Physiol ; 288: F703 - F713. Franco Onofri, et, al. (2000) J. Biol. Chem ; 275: 29857. Dario Bonanomi, et, al. (2005) J. Neurosci; 25: 7299 - 7308. Hiroshi Tokumitsu, et, al. (2005) J. Biol. Chem ; 280: 35108 - 35118.
Immunogen
synapsin (Ab-9) antibody was raised against a peptide sequence around aa.7~11 (R-L-S-D-S) derived from Human SYN1/synapsin.