Application
Antibody used in IHC on Human Skin.Application
Antibody used in WB on Human HepG2 at 0.5 ug/ml.| Product Name | TAPBP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TAPBP, NGS17, TAPA, TPN, TPSN |
| Product description | TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.1) Facoetti, A., (2005) Clin. Cancer Res. 11 (23), 8304-8311. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TAPBP. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| TAPBP antibody can be used for detection of TAPBP by ELISA at 1:12500. TAPBP antibody can be used for detection of TAPBP by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TAPBP |
|---|---|
| Alternative Names | TAPBP NGS17 TAPA TPN TPSN |
| Molecular Weight(MW) | 46 kDa, 44 kDa |
Application
Antibody used in IHC on Human Skin.
Application
Antibody used in WB on Human HepG2 at 0.5 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | TAPBP antibody can be used for detection of TAPBP by ELISA at 1:12500. TAPBP antibody can be used for detection of TAPBP by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TAPBP antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
