Application
Immunohistochemistry staining of TARBP2 in brain cortex tissue using TARBP2 Antibody.| Product Name | TARBP2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TARBP2, TAR RNA binding protein 2, TRBP1, TRBP2, TAR RNA-binding protein 2, TRBP, LOQS |
| Product description | Principal Names: TAR (HIV) RNA-binding protein 2; HIV-Transactivating response RNA-binding protein; TRBP; Official Gene Symbol: TARBP2 TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis. |
| Immunogen | A portion of amino acids 150-200 of human TRBP2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| TARBP2 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
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| Species Reactivity | BovineChimpanzeeHumanMouseRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TARBP2 |
|---|---|
| Alternative Names | TARBP2 TAR RNA binding protein 2 TRBP1 TRBP2 TAR RNA-binding protein 2 TRBP LOQS |
| Tissue Specificity | The amino acid sequence used as immunogen is 100% homologous in human (isoforms a and b), mouse, rat, bovine, chimp, and zebrafish. Human isoform a is a 366 amino acid protein, and human isoform b is a 345 amino acid protein. |
Application
Immunohistochemistry staining of TARBP2 in brain cortex tissue using TARBP2 Antibody.| Application Notes | TARBP2 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
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| Form | Liquid |
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| Storage Instructions | TARBP2 antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.2% gelatin, 0.05% sodium azide. |
