Application
Western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstdetected the TBCC protein (arrow).| Product Name | TBCC Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Tubulin-specific chaperone C, Tubulin-folding cofactor C, CFC, TBCC |
| Product description | Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.1) Hage-Sleiman, R., et al. BMC Cancer 10, 135 (2010) : |
| Immunogen | This TBCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human TBCC. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TBCC |
|---|---|
| Alternative Names | Tubulin-specific chaperone C Tubulin-folding cofactor C CFC TBCC |
| Molecular Weight(MW) | 39 kDa |
Application
Western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstdetected the TBCC protein (arrow).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
