Application
Western blot analysis of TBX21 in 293 cell lysate with TBX21 antibody at 1 μg/ml.Application
Immunofluorescence of TBX21 in 293 cells with TBX21 antibody at 5 μg/mL.| Product Name | TBX21 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TBX21 Antibody : TBET, T-PET, T-bet, TBLYM, TBET, T-box transcription factor TBX21, T-cell-specific T-box transcription factor T-bet, T-box protein 21 |
| Product description | TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box (1,2). Members of this family include transcription factors involved in the regulation of developmental processes (2). Studies in mouse and humans show that TBX21 is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (1,3). Expression of the human ortholog also correlates with interferon-gamma expression in Th1 and natural killer cells, suggesting a TBX21 may play a role in initiating Th1 lineage development from naive Th precursor cells. (3).1) Szabo SJ, Kim ST, Costa GL, et al. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000; 100:655-69. |
| Immunogen | TBX21 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TBX2. The immunogen is located within the last 50 amino acids of TBX21 . |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFWB |
| TBX21 antibody can be used for detection of TBX21 by Western blot at 1 - 2 μg/ml.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TBX21 |
|---|---|
| Alternative Names | TBX21 Antibody : TBET T-PET T-bet TBLYM TBET T-box transcription factor TBX21 T-cell-specific T-box transcription factor T-bet T-box protein 21 |
| Molecular Weight(MW) | Predicted: 59 kDa Observed: 55kDa |
| Sequence Similarities | 2) Cat. No. 17-010 - HEK293 Cell Slide |
| Tissue Specificity | TBX21 antibody is human and mouse reactive. |
Application
Western blot analysis of TBX21 in 293 cell lysate with TBX21 antibody at 1 μg/ml.
Application
Immunofluorescence of TBX21 in 293 cells with TBX21 antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1210 - HEK293 Cell Lysate |
|---|---|
| Application Notes | TBX21 antibody can be used for detection of TBX21 by Western blot at 1 - 2 μg/ml.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TBX21 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | TBX21 Antibody is supplied in PBS containing 0.02% sodium azide. |
