Application
Antibody used in IHC on Human Skeletal Muscle.Application
Antibody used in IHC on Human kidney.Application
Antibody used in WB on Human Liver at 0.2-1 ug/ml.| Product Name | TBX21 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TBX21, HGNC:11599, T-PET, T-bet, TBLYM, TBET |
| Product description | TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.1) Sasaki, Y., et al., (2004) Hum. Genet. 115 (3), 177-184. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX21. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| TBX21 antibody can be used for detection of TBX21 by ELISA at 1:312500. TBX21 antibody can be used for detection of TBX21 by western blot at 1.0-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TBX21 |
|---|---|
| Alternative Names | TBX21 HGNC:11599 T-PET T-bet TBLYM TBET |
| Molecular Weight(MW) | 58 kDa |
Application
Antibody used in IHC on Human Skeletal Muscle.
Application
Antibody used in IHC on Human kidney.
Application
Antibody used in WB on Human Liver at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1304 - Human Liver Tissue Lysate |
|---|---|
| Application Notes | TBX21 antibody can be used for detection of TBX21 by ELISA at 1:312500. TBX21 antibody can be used for detection of TBX21 by western blot at 1.0-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store TBX21 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
