T-box transcription factor TBX3, T-box protein 3, TBX3
Product description
This gene is a member of a phylogenetically conserved
family of genes that share a common DNA-binding domain, the T-box.
T-box genes encode transcription factors involved in the regulation
of developmental processes. This protein is a transcriptional
repressor and is thought to play a role in the anterior/posterior
axis of the tetrapod forelimb. Mutations in this gene cause
ulnar-mammary syndrome, affecting limb, apocrine gland, tooth,
hair, and genital development. Alternative splicing of this gene
results in three transcript variants encoding different isoforms;
however, the full length nature of one variant has not been
determined.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This TBX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human TBX3.
Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.