T-box transcription factor TBX4, T-box protein 4, TBX4
Product description
This gene is a member of a phylogenetically conserved
family of genes that share a common DNA-binding domain, the T-box.
T-box genes encode transcription factors involved in the regulation
of developmental processes. This gene is the human homolog of mouse
Tbx4, which is closely linked to Tbx2 on mouse chromosome 11.
Similarly this gene, like TBX2, maps to human chromosome 17.
Expression studies in mouse and chicken show that Tbx4 is expressed
in developing hindlimb, but not in forelimb buds, suggesting a role
for this gene in regulating limb development and specification of
limb identity.1) Kim, J.J., et al. J. Hum. Genet. 55(1):27-31(2010)
Immunogen
This TBX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-129 amino acids from the N-terminal region of human TBX4.
Western blot analysis in A549,mouse NIH/3T3 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.