Application
Western blot analysis of THAP11 in human brain tissue lysate with THAP11 antibody at 1 μg/ml.| Product Name | THAP11 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | THAP11 Antibody: RONIN, CTG-B43a, CTG-B45d, HRIHFB2206, THAP domain-containing protein 11 |
| Product description | The THAP domain-contining protein 11 (THAP11), also known as Ronin, is an essential factor involved in embryonic stem (ES) cell pluripotency and cell growth (1). THAP 11 contains a THAP domain, a conserved DNA-binding domain common to many proteins associated with chromatin modification and gene expression silencing, and has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases (2). THAP11 can also negatively regulate CD44 v6 expression through its interaction with the poly(rC) binding protein PCBP1 (3).1) Dejosez M, Krumenacker JS, Zitur LJ, et al. Ronin is essential for embryogenesis and the pluripotency of mouse ES cells. Cell 2008; 133:1162-74. |
| Immunogen | THAP11 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THAP11. The immunogen is located within the last 50 amino acids of THAP11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| THAP11 antibody can be used for detection of THAP11 by Western blot at 1 - 2 μg/ml.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | THAP11 |
|---|---|
| Alternative Names | THAP11 Antibody: RONIN CTG-B43a CTG-B45d HRIHFB2206 THAP domain-containing protein 11 |
| Molecular Weight(MW) | Predicted: 35 kDa Observed: 38 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (100%) |
| Tissue Specificity | THAP11 antibody is human, mouse and rat reactive. |
Application
Western blot analysis of THAP11 in human brain tissue lysate with THAP11 antibody at 1 μg/ml.| Positive Control | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
|---|---|
| Application Notes | THAP11 antibody can be used for detection of THAP11 by Western blot at 1 - 2 μg/ml.: |
| Form | Liquid |
|---|---|
| Storage Instructions | THAP11 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | THAP11 antibody is supplied in PBS containing 0.02% sodium azide. |
