Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using Tip60 (Phospho-Ser90) antibody (left) or the same antibody preincubated with blocking peptide (right).| Product Name | Tip60 (phospho Ser90) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HTATIP, TI60, Tat-interactive protein-60 |
| Product description | The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.1) Kamine J., Virology 216:357-366(1996). |
| Immunogen | Tip60 (phospho Ser90) antibody was raised against a peptide sequence around phosphorylation site of Serine 90 (P-G-S (p)-P-E) derived from Human Tip60. |
| Modification | p-Ser90 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KAT5 |
|---|---|
| Alternative Names | HTATIP TI60 Tat-interactive protein-60 |
| Molecular Weight(MW) | 58 kDa |
| Tissue Specificity | The antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90. |
| Entrez Gene | 10524 |
|---|---|
| Protein Accession | NP_006379.2 |
Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using Tip60 (Phospho-Ser90) antibody (left) or the same antibody preincubated with blocking peptide (right).| Application Notes | IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
