TIPIN is required for normal progression of S-phase. It is important for cell survival after DNA damage or replication stress and may be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.1) Ozelius, L.J., (2007) Mol. Cell. Biol. 27 (8), 3131-3142.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TIPIN.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
TIPIN antibody can be used for detection of TIPIN by ELISA at 1:1562500. TIPIN antibody can be used for detection of TIPIN by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
TIPIN antibody can be used for detection of TIPIN by ELISA at 1:1562500. TIPIN antibody can be used for detection of TIPIN by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TIPIN antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt