Application
Western blot analysis of TLX2 in rat brain tissue lysate with TLX2 antibody at (A) 0.5 and (B) 1 μg/mL.Application
Immunofluorescence of TLX2 in rat brain tissue with TLX2 antibody at 20 μg/ml.Application
Immunohistochemistry of TLX2 in rat brain tissue with TLX2 antibody at 2.5 μg/ml.| Product Name | TLX2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TLX2 Antibody: NCX, HOX11L1, NCX, T-cell leukemia homeobox protein 2, Homeobox protein Hox-11L1 |
| Product description | TLX2 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.1) Dear TN, Sanchez-Garcia I, and Rabbitts TH, et al. The Hox11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes. Proc. Natl. Acad. Sci. USA 1993; 90:4431-5. |
| Immunogen | TLX2 antibody was raised against an 18 amino acid peptide near the amino terminus of human TLX2. The immunogen is located within amino acids 20 - 70 of TLX2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| TLX2 antibody can be used for detection of TLX2 by Western blot at 0.5 - 1 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TLX2 |
|---|---|
| Alternative Names | TLX2 Antibody: NCX HOX11L1 NCX T-cell leukemia homeobox protein 2 Homeobox protein Hox-11L1 |
| Molecular Weight(MW) | Predicted: 31 kDa Observed: 30 kDa |
| Tissue Specificity | TLX2 antibody is predicted to not cross-react with other TLX proteins. |
Application
Western blot analysis of TLX2 in rat brain tissue lysate with TLX2 antibody at (A) 0.5 and (B) 1 μg/mL.
Application
Immunofluorescence of TLX2 in rat brain tissue with TLX2 antibody at 20 μg/ml.
Application
Immunohistochemistry of TLX2 in rat brain tissue with TLX2 antibody at 2.5 μg/ml.| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | TLX2 antibody can be used for detection of TLX2 by Western blot at 0.5 - 1 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TLX2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | TLX2 Antibody is supplied in PBS containing 0.02% sodium azide. |
