Application
Western blot analysis of TMEM135 in rat liver tissue lysate with TMEM135 antibody at (A) 1 and (B) 2 μg/mL.Application
Immunofluorescence of TMEM135 in human liver tissue with TMEM135 antibody at 20 μg/ml.Application
Immunohistochemistry of TMEM135 in human liver tissue with TMEM135 antibody at 2.5 μg/ml.| Product Name | TMEM135 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TMEM135 Antibody: PMP52, Transmembrane protein 135, Peroxisomal membrane protein 52, PMP52 |
| Product description | TMEM135 Antibody: The transmembrane protein 135 (TMEM135), also known as peroxisomal membrane protein 52 (PMP52), was initially identified as a protein that might be critical for adipogenesis and osteoblastogenesis. Further studies have indicated that TMEM135 may be part of a regulatory circuit that plays an important role in fat metabolism and energy expenditure in both C. elegans as well as mammalian organisms. Finally, recent experiments has suggested that TMEM135 may be an additional driver of breast cancer.1) Scheideler M, Elabd C, Zaragosi LE, et al. Comparative transcriptomics of human multipotent stem cells during adipogenesis and osteoblastogenesis. BMC Genomics 2008; 9:340. |
| Immunogen | TMEM135 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TMEM135 . The immunogen is located within the last 50 amino acids of TMEM135. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| TMEM135 Antibody can be used for detection of TMEM135 by Western blot starting at 1 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TMEM135 |
|---|---|
| Alternative Names | TMEM135 Antibody: PMP52 Transmembrane protein 135 Peroxisomal membrane protein 52 PMP52 |
| Molecular Weight(MW) | Predicted: 50 kDa Observed: 53 kDa |
| Sequence Similarities | 2) Cat. No. 10-201 - Human Liver Tissue Slide |
| Tissue Specificity | At least two isoforms of TMEM135 are known to exist; this antibody will detect both isoforms. |
Application
Western blot analysis of TMEM135 in rat liver tissue lysate with TMEM135 antibody at (A) 1 and (B) 2 μg/mL.
Application
Immunofluorescence of TMEM135 in human liver tissue with TMEM135 antibody at 20 μg/ml.
Application
Immunohistochemistry of TMEM135 in human liver tissue with TMEM135 antibody at 2.5 μg/ml.| Positive Control | 1) Cat. No. 1464 - Rat Liver Tissue Lysate |
|---|---|
| Application Notes | TMEM135 Antibody can be used for detection of TMEM135 by Western blot starting at 1 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TMEM135 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | TMEM135 Antibody is supplied in PBS containing 0.02% sodium azide. |
