This gene encodes beta-tropomyosin, a member of the actin
filament binding protein family, and mainly expressed in slow, type
1 muscle fibers. Mutations in this gene can alter the expression of
other sarcomeric tropomyosin proteins, and cause cap disease,
nemaline myopathy and distal arthrogryposis syndromes.
Alternatively spliced transcript variants encoding different
isoforms have been found for this gene.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This TPM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-280 amino acids from the C-terminal region of human TPM2.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.