Triggering receptor expressed on myeloid cells 2, TREM-2, Triggering receptor expressed on monocytes 2, TREM2
Product description
TREM2 is a membrane protein
that forms a receptor signaling complex with TYROBP. The encoded
protein may be involved in chronic inflammation by triggering the
production of constitutive inflammatory cytokines. Defects in this
gene are a cause of polycystic lipomembranous osteodysplasia with
sclerosing leukoencephalopathy (PLOSL).1) Stefano, L., et al. J. Neurochem. 110(1):284-294(2009)
Immunogen
This TREM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human TREM2.
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.