Application
Western blot analysis of TRIP6 in A431 cell lysate with TRIP6 antibody at 1 μg/mL.Application
Immunofluorescence of TRIP6 in HeLa cells with TRIP6 antibody at 20 μg/mL.Application
Immunocytochemistry of TRIP6 in HeLa cells with TRIP6 antibody at μg/mL.| Product Name | TRIP6 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRIP6 Antibody: OIP1, OIP-1, ZRP-1, TRIP-6, TRIP6i2, OIP1, Thyroid receptor-interacting protein 6, Opa-interacting protein 1, TR-interacting protein 6 |
| Product description | TRIP6 Antibody: TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-κB activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.1) Murthy KK, Clark K, Fortin Y, et al. ZRP-1, a zyxin-related protein, interacts with the second PDZ domain of the cytosolic protein tyrosine phosphatase hPTP1E. J. Biol. Chem.1999; 274:20679-87. |
| Immunogen | TRIP6 antibody was raised against a 15 amino acid synthetic peptide near the center of human TRIP6. The immunogen is located within amino acids 190 - 240 of TRIP6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICCIFWB |
| TRIP6 antibody can be used for detection of TRIP6 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TRIP6 |
|---|---|
| Alternative Names | TRIP6 Antibody: OIP1 OIP-1 ZRP-1 TRIP-6 TRIP6i2 OIP1 Thyroid receptor-interacting protein 6 Opa-interacting protein 1 TR-interacting protein 6 |
| Sequence Similarities | 2) Cat. No. 17-001 - HeLa Cell Slide |
Application
Western blot analysis of TRIP6 in A431 cell lysate with TRIP6 antibody at 1 μg/mL.
Application
Immunofluorescence of TRIP6 in HeLa cells with TRIP6 antibody at 20 μg/mL.
Application
Immunocytochemistry of TRIP6 in HeLa cells with TRIP6 antibody at μg/mL.| Positive Control | 1) Cat. No. 1202 - A431 Cell Lysate |
|---|---|
| Application Notes | TRIP6 antibody can be used for detection of TRIP6 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TRIP6 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | TRIP6 Antibody is supplied in PBS containing 0.02% sodium azide. |
