Application
Western blot analysis of lysed extracts from mouse brain tissue using TrkB (Phospho-Tyr705).| Product Name | TrkB (phospho Tyr705) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRKB, trk-B, GP145-TrkB, P53, BDNF/NT-3 growth factors receptor precursor, EC 2.7.10.1, GP145-TrkB/GP95-TrkB, NTRK2 |
| Product description | Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC γ1.1) Woronowicz A, et al. Glycobiology. 2007 Jan;17 (1): 10-24. Mojsilovic-Petrovic J, et al. J Neurosci. 2006 Sep 6;26 (36): 9250-63. Lewis MA, et al. Mol Pharmacol. 2006 Apr;69 (4): 1396-404. Cai D, et al. Physiol Genomics. 2006 Feb 14;24 (3): 191-7. |
| Immunogen | TrkB (Phospho-Tyr705) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 705 (T-D-Y P-Y-R) derived from Human TrkB. |
| Modification | p-Tyr705 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NTRK2 |
|---|---|
| Alternative Names | TRKB trk-B GP145-TrkB P53 BDNF/NT-3 growth factors receptor precursor EC 2.7.10.1 GP145-TrkB/GP95-TrkB NTRK2 |
| Molecular Weight(MW) | 140 kDa |
| Tissue Specificity | This antibody detects endogenous level of TrkB only when phosphorylated at tyrosine 705. |
| Entrez Gene | 4915 |
|---|---|
| Protein Accession | NP_001007098.1 |
Application
Western blot analysis of lysed extracts from mouse brain tissue using TrkB (Phospho-Tyr705).| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
