Application
Western blot analysis of TSC22D3 in human small intestine tissue lysate with TSC22D3 antibody at (A) 1 and (B) 2 μg/mL.Application
Immunofluorescence of TSC22D3 in human small intestine tissue with TSC22D3 antibody at 20 μg/ml.Application
Immunohistochemistry of TSC22D3 in human small intestine tissue with TSC22D3 antibody at 5 μg/ml.| Product Name | TSC22D3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TSC22D3 Antibody: DIP, GILZ, hDIP, DSIPI, TSC-22R, TSC22 domain family protein 3, DSIP-immunoreactive peptide, Protein DIP |
| Product description | TSC22D3 Antibody: The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-κB and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-κB. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.1) Riccardi C, Cifone MG, and Migliorati G. Glucocorticoid hormone-induced modulation of gene expression and regulation of T-cell death: role of GITR and GILZ, two dexamethasone-induced genes. Cell Death Differ. 1999; 6:1182-9. |
| Immunogen | Rabbit polyclonal TSC22D3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TSC22D3. The immunogen is located within amino acids 40 - 90 of TSC22D3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| TSC22D3 antibody can be used for detection of TSC22D3 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TSC22D3 |
|---|---|
| Alternative Names | TSC22D3 Antibody: DIP GILZ hDIP DSIPI TSC-22R TSC22 domain family protein 3 DSIP-immunoreactive peptide Protein DIP |
| Molecular Weight(MW) | Predicted: 22 kDa Observed: 23 kDa |
| Sequence Similarities | 2) Cat. No. 11-801 - Human Small Intestine Tissue Slide |
Application
Western blot analysis of TSC22D3 in human small intestine tissue lysate with TSC22D3 antibody at (A) 1 and (B) 2 μg/mL.
Application
Immunofluorescence of TSC22D3 in human small intestine tissue with TSC22D3 antibody at 20 μg/ml.
Application
Immunohistochemistry of TSC22D3 in human small intestine tissue with TSC22D3 antibody at 5 μg/ml.| Positive Control | 1) Cat. No. 1308 - Human Small Intestine Tissue Lysate |
|---|---|
| Application Notes | TSC22D3 antibody can be used for detection of TSC22D3 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TSC22D3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | TSC22D3 Antibody is supplied in PBS containing 0.02% sodium azide. |
