TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5).1) Claus, M., (2005) Endocrinology 146 (12), 5197-5203.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TSHR.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
TSHR antibody can be used for detection of TSHR by ELISA at 1:1562500. TSHR antibody can be used for detection of TSHR by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
TSHR antibody can be used for detection of TSHR by ELISA at 1:1562500. TSHR antibody can be used for detection of TSHR by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TSHR antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.