Application
Western Blot at 1:2000 dilution + PC-3 whole cell lysate Lysates/proteins at 20 ug per lane.| Product Name | TXNRD1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Thioredoxin reductase 1, cytoplasmic, TR, 1.8.1.9, Gene associated with retinoic and interferon-induced mortality 12 protein, GRIM-12, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-102-derived reductase-like factor, Thioredoxin red |
| Product description | Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.1) Gasdaska P.Y.,et al.FEBS Lett. 373:5-9(1995). |
| Immunogen | This TXNRD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 271-305 amino acids from the Central region of human TXNRD1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:2000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TXNRD1 |
|---|---|
| Alternative Names | Thioredoxin reductase 1 cytoplasmic TR 1.8.1.9 Gene associated with retinoic and interferon-induced mortality 12 protein GRIM-12 Gene associated with retinoic and IFN-induced mortality 12 protein KM-102-derived reductase-like factor Thioredoxin red |
| Molecular Weight(MW) | 71 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine |
Application
Western Blot at 1:2000 dilution + PC-3 whole cell lysate Lysates/proteins at 20 ug per lane.| Application Notes | For WB starting dilution is: 1:2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
