Ubiquitin-like modifier-activating enzyme 6, Ubiquitin-activating enzyme 6, Monocyte protein 4, MOP-4, Ubiquitin-activating enzyme E1-like protein 2, E1-L2, UBA6, MOP4, UBE1L2
Product description
Modification of proteins with ubiquitin (UBB; MIM 191339)
or ubiquitin-like proteins controls many signaling networks and
requires a ubiquitin-activating enzyme (E1), a ubiquitin
conjugating enzyme (E2), and a ubiquitin protein ligase (E3).
UBE1L2 is an E1 enzyme that initiates the activation and
conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed
17597759]).1) Groettrup, M., et al. Trends Biochem. Sci. 33(5):230-237(2008)
Immunogen
This UBA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 861-889 amino acids from the C-terminal region of human UBA6.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.