Application
Immunohistochemistry staining of UBE2V1 in thyroid tissue using UBE2V1 Antibody.| Product Name | UBE2V1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UBE2V1, CROC1, UEV1, UBE2V, UEV-1, UEV1A, CROC-1 |
| Product description | The E2 enzyme, Ubc13, and the E2 enzyme variants, Uevs, form stable, high affinity complexes for the assembly of Lys63-linked ubiquitin chains. This complex has been shown to activate NF-κB signaling pathway by linking TRAF6 to IKKs. Blockade of this polyubiquitin chain synthesis, but not inhibition of the proteasome, prevents the activation of IKK by TRAF6. These results suggest a new regulatory function for ubiquitin, in which IKK is activated through the assembly of Lys63-linked polyubiquitin chains. The UEV proteins are also involved in the control of differentiation. This antibody may recognize isoform UBE2V1b. |
| Immunogen | UBE2V1 antibody was raised against amino acids 31 - 49 of UBE2V1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| UBE2V1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | UBE2V1 |
|---|---|
| Alternative Names | UBE2V1 CROC1 UEV1 UBE2V UEV-1 UEV1A CROC-1 |
| Tissue Specificity | A protein band of approximate molecular weight of 20 kD can be seen in Jurkat, RAW and HeLa cell lysates. This may also recognize isoform b of UBE2V1. |
Application
Immunohistochemistry staining of UBE2V1 in thyroid tissue using UBE2V1 Antibody.| Application Notes | UBE2V1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | UBE2V1 antibody can be stored short term 4 ˚C. For long term storage aliquot and store at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.2% gelatin, 0.05% sodium azide. |
